Adult progeria Werner syndrome (WS), a rare autosomal recessive disorder, is characterized by accelerated aging symptoms after puberty.The causative gene, WRN, is a member of the RecQ DNA helicase Tobacco family and is predominantly involved in DNA replication, repair, and Coverless Duvet telomere maintenance.Here, we report the generation of iPS c
Danielle Abrams’s performance art critically engages with late twentieth-century debates on race, queerness, and identity, positioning her as a vital figure in challenging monolithic and heteronormative structures of identity.Her early work Quadroon (1998), a live performance and four-channel video installation blending music, costume, Trifle Bow
During epigenetic reprogramming germ cells activate alternative mechanisms to maintain the repression retrotransposons.This mechanism involves the recruitment of genome defence proteins such as MAEL, PIWIL4 and TDRD9, which associate with piRNAs and promote Line-1 silencing.MAEL, PIWIL4 and TDRD9 form the piP-bodies, which organization and dynamics